One Pot Synthesis of 1, 4 Dihydropyridine Derivatives by IR Irradiation
نویسندگان
چکیده
In the presence of IR irradiation by the use of solid support montmorillonite KSF, under solvent free conditions four component aldehyde, Dione, Meldrum acid and ammonium acetate react for the formation of 1, 4 dihydropyridine derivatives. This is a greener method and one pot synthesis. Minimum reaction time and higher yield are the advantages of this process. The product can be purifying by chromatographic method. The synthesized compounds were also found effective against bacterial and fungal organism. We can use these derivatives for the treatment of disease as an antibacterial and antifungal agent. Key words1,4dihydropyridine, IR irradiation, solvent free synthesis, Multicomponent
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